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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14834d165d6cc1c465a5b81d5b1637f96cdd4e925d1f8584762028048ad49df4' 
  AND token = 'o0LqlXuDnOdLZfhBmEYcIT3UcOirVYTwgJxVR8d0c4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}