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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a10e38a96f76478694436a18bed7237746dde84942229b0d09137388c1702064' 
  AND token = 'Ec6DsmDoOegWXGDz0ZC8LIoQVgl6iWBm4MhffEkp96o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}