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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7126fc0105046be976f684f7906d7cd7452f0de028b6e189f3a69c04c4e2542b' 
  AND token = 'gTv6uItyQj59uNs7pe/I7mm9D0+5aESOWHLZsPRhON8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}