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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aa8ff4c904a731bc14b4701ce7f07470569ed5cab0a3ce50aebb93b04e62520' 
  AND token = 'Oxy8mHXdK/1GvqxUiASUhAnrjRE4s8vMbC38dQxS/5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}