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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a497e061922e386842159f33413e88bb5654887f1ae9944c81e0c9a50e18ce57' 
  AND token = 'qrnZTbAvmDdx9WdpqzCPy3+ZQnK5LqZZnympxMETAio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}