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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1b1d7e542911278eee41ceee5445256bba53be6e49c4fe85c6e0c3fec3e5b0' 
  AND token = '5ZRZFc1WFADD9kLSSRDalTjGGnLdAQjgSUfxP+MObOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}