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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49025126a3947253444dc71ffe1536138a1074ed82d7b453f630c8a097c3f9ed' 
  AND token = 'yT+aPeR8ZUMvqKxmLUEebn+oCDKTlyeDxr9h5L4ghGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}