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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dcfbbd1e4e29629037a0ca7d5d6797bf0028c3ebb1c7c8f370d9384ca913259' 
  AND token = 'Ri+nShm7hp5MEgdCdSgk1mX7OoCAeEDgFuItKwu75Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}