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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9adc7d565048b2da0f4b7b0589427d459054f9a1b49b4ef0273e7da883a3d359' 
  AND token = 'k9HIMG8SgGlXAsFUncNROlM2vjCgyPbQcIXmGvkjpG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}