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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58d39c77b60b0c4119bedec7290d1cadf257115bd8bd78a4b4b15721858422d8' 
  AND token = 'hys1tLoKzBb7rSu8WB7HqY3cJ1kdlHTPddfcC7rIIJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}