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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d67c9caf3440f55ff63e9e5e2c6c831866e872feae5e29ffe1da3e5a01bca1a' 
  AND token = 'iEwBjLvQMDJ06iDYR4BgTYfZexfDdMw0sIznFbBrdS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}