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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5b05dad21e452152fbeee8e1cdb0f6ff8fae5e7c64811250d53dcb5db7029c' 
  AND token = 'x+wA/ZNNWea6XtoWBJjlbRImTA0HYAyBbNgsE8prthM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}