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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd546e4fb2336d2335dc511048203974d653d3601ff05f672523227f5b427639e' 
  AND token = '8h2p6CPBAoVDxY3CZRYdxdv+nK4GYPkzu2hThhy9s+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}