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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd76fdbf9192f64c93758018ae398cddb24b275b636921416cbe78487f0553485' 
  AND token = 'AcNfIjZ1z0C9RPc2eLrACokeT3+MfknJ62pO3I9TZ3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}