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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17ef67ee2f74d9f0b8f69387e67a3c4e0ce953d33b109d9034fde1648f4b6166' 
  AND token = 'JaSeJ/76903UXDsmtCDW+mGRp9Tl1M9TEVSsvha7p88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}