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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c49bf40e4dd2860aa5de3d393387f162012fff3860288b192f487bb4732b992' 
  AND token = 'fI8ubMeZMyoCdxCgqihgx7eDAd4+5aty9NakC48e76U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}