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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ec077a35c83d1590325c620d19e91308ff07974388a50db7b1653937c1abcb2' 
  AND token = 'o+CAzi1NxfpzktxvGTPal/yrFgi7zQlKQDk/dh/OBOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}