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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f784251f71f8f2ef805a058eaf13b9e86b0ae948f243dec587dd5260bb6d85a' 
  AND token = 'ezx2mqGRSHqt9DO5oYYqVWPnWK8qjsmcV/gkoyz0lok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}