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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa2b84cfb319c7dbf3ffab9030a1690beeedbe4ed50f21d6982fcca0451b38aa' 
  AND token = 'Em9ynhNNEY9oYvdE0TXmya0Cs4Ui5EGtTGFQ7YeWFME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}