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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387ff5003b35a40b5cacf3912e3bf37331a30e951a3c673518b8e98332b9891e' 
  AND token = '5asY1bee+ne9tN1FLhoSt87qA8EW7RptjylMhPYWmXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}