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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c365d7a9125718415dfa925b6cfcdbda8aa01b827c66e4e22bcc28ed5efdc3a2' 
  AND token = 'ksgtx8rMyRqVNPf/XDdU0UNrWp7m28lqz/Jxx6iZpwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}