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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33328144b245329936f5b6d57dab701e1a667bd401f3b7d34bf5a08ee6da3d63' 
  AND token = 'vaWey1dHoGhqhU9QZ/hAk+2w38YqDWtA/eFnO+R2QpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}