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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16aa57ec31f078dbfb4f969998f6c3ad3f801ee5592cee65bb5184fa994e738d' 
  AND token = 'KUdRe+gJ1WapY8OwR8BzR6jy4hwxKsR5+ixU9OFTzP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}