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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25769756d56b723c1bbf769a7cf90a1a2d1140c0d536dde938d549c48321357' 
  AND token = 'MpbidT7YrbLxTHb/CVliAabmDIEUguXqfivIALCLpxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}