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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45da0649b8d479aeb7e84f2aa9b35569b7453e78bd418baee8757bca52f7cbf0' 
  AND token = 'NfgpTt07M6IG8AgDGzE2iUT0Sf+/9OLKCPpwzD20uz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}