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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43d34e1af35ed1453b633189e24fae9e941a89150a20a753dcbf5bb96887686' 
  AND token = 'vkHLC6b8hAiPfyY/kABxKDDOwjlx/shWV6CaCOflKWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}