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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb64b87c5a65903f04356ac6c4c85f7c6ef314ff0f4074b959d09ea2b29b7e59' 
  AND token = '+C2W6C3EuEQ1b97TCmEohrebbTJTNo/4zTlWeY6f6Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}