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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9dd56c781df12dedf78c4087d5a51e27163dec437ac64599e5533acd5a6c0ad' 
  AND token = '407yx9IOTRj5mB78Y+8c+3u+ANMAVH5hUoMXMq14gw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}