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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6e62b78eb7690ebf2451d7a3153a925cb6756b56270273d37833bdeb76d755' 
  AND token = 'Wq9z/tsOfFddyG0MEZWWqMZSFfGAycG3Qmmm+KCrzDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}