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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e9a64c55604b0d6174ab6a3ce2f3db04a81e5d5dd22c79d8f2646c6d509c75c' 
  AND token = 'xLoabDBeU6O96S48asAFlW7pfzyo3wkBhZEG8fOL3G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}