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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b307de219fcdafa2028e9a85c780167dcdc4e5a0f18faddd58a8aee456b1b1' 
  AND token = 'qn5XJg53CunFKNtodk8hCkEpqq9WFfqok6wBw0I6MiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}