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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cfe4729c0a487918d2e1ef6cdcdaa2fa41fb9e9272f43028d70926a4cd18619' 
  AND token = 'mCTMSvl7d7kgN4syu6zynD0S0BmGnPO0yEVLL93y2KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}