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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148527d22d965873b343ba11b4bd968f1727c61fc421415e727271245573576a' 
  AND token = 'hPfLU7/v36exigkQ+eP2YdfJLw89ux8DZHEui9RKSb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}