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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f7c970364f68f7ed4afb4a6e9615da6e49ac4a4c98b256450a8cc7006d793c' 
  AND token = 'ZEo/Z16a5sLvrvKomvwtpZxYso5k39LACS1/dhu+5PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}