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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6740eca895bed6290f14edffde030088415fbe2068fb4a1e5247e5b7d224edb3' 
  AND token = 'lqjKMwCzCx1oCsIJ+7iosP5JdpGMzM2pmpbTrm0PrcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}