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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20da0c00c5e4ea2b14ba2f1599b4ecdc89041bc21d969d32d7fd53bc3bb5419f' 
  AND token = '6GxHESDm+w94Uc+K7t4ZJfvTDeTtCin69njP/tHU0M8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}