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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01cc6352c5a94aed92bc737db97138845657c8c405a4249b7b916ef9a83b2c88' 
  AND token = '2OYURtnDKSndJCGQA7q9TKNmnPfjtm8O0QVZjKcDS6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}