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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a602618ea9ddda4b7169c53e9128186a3e0ac5625ea512a1016bbe6d4871f20' 
  AND token = 'Z/mDhNpS36PJc/ZP8yWK1BXcVB8EbRtv2Zz5jO7kRQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}