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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de97155ee7870f3f4a7023ad1410f43bebe0b875da10f9a41226fe43d55c27b8' 
  AND token = 'HCH3/8kv6zc6t6NXUSeKulcSSa7BHgOo0b9hAFID/v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}