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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20200099b7fd2bb24a4940eb525d7314a936e800d3d08eeddd9aa57254751a11' 
  AND token = 'oB/W48HxnwbQwDAtSHkl1EG9zoDxx0McxShdLNmb3sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}