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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ad33340456d00d13b5832f13c76c188394fa6ed44e6c578164934a8efe615b' 
  AND token = 'iqLyRP220Mju0B2i/kHjdTKAjDkJX2JN+IsNQ5MFDcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}