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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e503067fcf85f174a41a7596e8098a003e6f6f05ef45beeb5905d063fa2cdd4' 
  AND token = 'T0/OH0do/uBJpSCjtK6t5m/uWazJPV4ldawhy2avYrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}