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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b2469c1cc6823c33db8aaea59e8f100e944e2a217fecb31ee67732db6c39d8' 
  AND token = 'yE29Uv+JUBZV4Hj5jevXpq03cEf0FI5KjDInB+3BNEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}