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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb7c2b1b5623e6041b3302212d2869cafbb727aba8762b57805a3dd5daf32473' 
  AND token = 'O4fkwVk6ls/HjhQe2QnTbB6SCVvHxPrMdTtfccmk6B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}