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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb1175e9ba98705c2bfcad3f7b5dca489ae12f468a4b376d0ee032e9b9b99354' 
  AND token = 'V7Gn5f15RDdxhqeZg7FmrMA0Ikd49NYOiG4OW1xWjEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}