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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07e24a3eb0725ff1c938a951ca1d89744b38d3434256f30c5f0a1ee7d93151fa' 
  AND token = 'iR4ZQySEsSoGK0xTXxW/u1jQLiiIL8s9rnBB4C+EETM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}