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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c18d525ffe968a03585cb3475cd22ed13bed6bdfb40a416e62a8f0ac53b9334b' 
  AND token = '5M+qsV7ICrvNus+FQcawN61xtzX3WZ8eqtFy1jPOSmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}