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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174586ccf6624a2f6d23a66dd4e39921477e415deff963c02f2a9cf1ab08dc80' 
  AND token = 'w0Qj8gAn2fJMEZtA7KpDyVDyuJt7uF+s3JqNNladzv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}