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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51fd78dcfdca97de18571aeda4184d62d522d18b947b02e3b036c93dbdb0737' 
  AND token = 'tfW/58P2PTBUXhnMbCnPl55z0AY41GrJnhZb5gOUP5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}