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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afda105fcfebae81c39cb92cd4fe6baeb4409d3ebbb20cdc52a69c24696ef98b' 
  AND token = 'NPHM+wnAHPhUKOVcB9z5y/R2pZ1RoCt3+ZiUF3buwDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}